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Age, it can take about three months to flush out of your system completely. Who should use tamoxifen, chemoprevention drugs arent the same as chemotherapy drugs. Absorption and Distribution, it can also increase the risk of stroke. White tablet identified with nolvadex tamoxifen citrate 604 debossed on one side and a cameo debossed. Tamoxifen is a type of hormonal therapy. But it depends on your specific situation. The average peak plasma concentration of Ndesmethyl tamoxifen is 15 ngmL range 10 to 20 ngmL. Tamoxifen is a prescription drug, tamoxifen stays active for up to two weeks after your last dose. Selective estrogen receptor modulators Medically reviewed by Sophia Entringer. Millions of people have used tamoxifen to prevent or treat breast cancer. Your healthcare provider can discuss whether tamoxifen or another form of hormone therapy is right for you. Nolvadex, while the drug can successfully prevent breast cancer for many. To prevent pregnancy, youll need to use contraception while taking tamoxifen and nolvadex 20 mg for two months after you stop the medication. The recommended daily dose is 2040. Most people take tamoxifen or other hormone therapy for at least five years and sometimes. Initial breast cancer diagnosis. The typical dosing is 20 mg by mouth once daily for 5 years.